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Learn More About the Science Behind Probiotics

You Are What You Absorb is an educational web site for healthcare practitioners and others interested in probiotics and wellness.
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Current Research on BB-12®

Examples of published scientific articles, documenting the effect of Chr. Hansen's Bifidobacterium BB-12®:

Abi-Hanna, A., Moore, N., Yolken, R., Saavedra, J. Long term consumption of infant formulas with live probiotic bacteria: safety and tolerance. 1998. J Pediatr Gastroenterol Nutr, 27 (4): 484.

Alm, L., Ryd-Kjellen, E., Setterberg, G., Blomquist, L. Effect of a new fermented milk product "CULTURA" on constipation in geriatric patients. 1993. 1st Lactic Acid Bacteria Computer Conference Proceedings. Horizon Scientific Press, Norfolk, England.

Anderson ADG, McNaught CE, Jain PK, MacFie J. 2004. Randomised clinical trial of synbiotic therapy in elective surgical patients. Gut, 53, 241-245.

Anderson ADG, McNaught CE, MacFie J, Tring I, Barker P, Mitchell CJ. 2003. Randomized clinical trial of multimodal optimization and standard perioperative surgical care. British Journal of Surgery, 90; 1497-1504.

Bin-Nun A, Bromiker R, Wilschanski M, Kaplan M, Rudensky B, Caplan M, Hammerman C. 2005. Oral probiotics prevent necrotizing enterocolitis in very low birth weight neonates. The Journal of Pediatrics 147: 192-196.

Black, F.T. Placebo-contolled double-blind trial of 4 lactobacilli strains (HIP) used as prophylactic agent against traveller's diarrhea (2 trials). 1996. Report by G. Nirnberger, Bioconsult, GmbH, Austria.

Black, F.T., Andersen, P.L., Laulund, S. Report from a double-blind placebo-controlled trial with HIP against traveler's diarrhea with a new dosage regimen. 1995. Internal report.

Black, F.T., Einarsson, K., Lidbeck, A., Orrhage, K., Nord, C.E. Effect of lactic acid producing bacteria on the human intestinal microflora during ampicillin treatment. 1991. Scand. J. Infect. Dis., 23: 247-254.

Black, F.T., Laulund, S. A study on the recovery of ingested, encapsulated Lactobacillus acidophilus and Bifidobacteria bifidum from doudenal fluid and faeces. 1988. Chr. Hansen Internal Report.

Black, F.T., Anderson, P.L., Orskov J., Orskov, F., Gaarslev, K., Laulund, S. Prophylactic efficacy of lactobacilli on traveler's diarrhea. 1989. Travel Medicine, 333-335.

Chouraqui JP, Van Egroo LD, Fichot MC. 2004. Acidified milk formula supplemented with bifidobacterium lactis: Impact on infant diarrhea in residential care settings. Journal of Pediatric Gastroenterology and Nutrition 38:288-292.

Collins JK, Clune Y, Meaney K, o'Donoghue M, Klinder A, Roller M, Karlsson P, Bennett M, O'Riordan M, Dunne C, O'Sullivan G, Rafter J, Watzl B, Rechkemmer G, Pool-Zobel BL. 2005. The influence of synbiotic consumption on cancer risk biomarkers in previously resected colon cancer subjects. Abstracts / Journal of Biotechnology 118S1: S1-1189.

Fukushima, Y., Kawata, Y., Hara, H., Terada, A., Mitsuoka, T. Effect of a probiotic formula on intestinal immunoglobulin A production in healthy children. 1998. International Journal of Food Microbiology, 42: 39-44.

Gatt M, Anderson ADG, Reddy BS, Hayward-Sampson P, tring IC, MacFie J. 2005. Randomized clinical trial of multimodal optimization of surgical care in patients undergoing major colonic resection. British Journal of Surgery, 92, 1354-1362.

Solauri, E., Arvola, T., Sutas, Y., Moilanen, E., Salminen, S. Probiotics in the management of atopic eczema. 2000. Clinical and Experimental Allergy, 30: 1604-1610.

Jain PK, McNaught CE, Anderson ADG, MacFie J, Mitchell CJ. 2004. Influence of synbiotic containing Lactobacillus acidophilus La5, Bifidobacterium lactic Bb12, Streptococcus thermophilus, Lactobacillus bulgaricus and oligofructose on gut barrier function and sepsis in critically ill patients: a randomised controlled trial. Clinical Nutrition 23; 467-475.

Kankaanpää, PE, Yang, B, Kallio, HP, Isolauri, E, Salminen, SJ. Influence of probiotic supplemented infant formula on composition of plasma lipids in atopic infants. 2002. Journal of Nutritional Biochemistry. 13: 364-369.

Kankaanpaa, P., Sutas, Y., Salminen, S., Isolauri, E. Results on clinical demonstraion of probiotics on children. Presented at Functional Food Research in Europe, Third Workshop, PROBDEMO, Finland, October 1-2, 1998.

Kirjavainen, PV, Arvola, T, Salminen, SJ, Isolauri, E. Aberrant composition of gut microbiota of allergic infants: a target of bifidobacterial therapy at weaning? 2002. Gut, 51: 51-55.


Laake K.O., Bjørneklett A., Aamodt G., Aabakken L., Jacobsen, M., Bakka, A., Vatn, M.H. 2005. Outcome of four weeks intervention with probiotics on symptoms and endoscopic appearance after surgical reconstruction with a J-configurated ileal-pouch-anal-anastomosis in ulcerative colitis. Scandinavian Journal of Gastroenterology (40) 43-51.

Laake, K.O., P.D. Line, K. Grzyb, G. Aamodt, L. Aabakken, A. Røset, A.B. Hvinden, A. Bakka, J. Eide, A. Bjørneklett, M.H. Vatn. 2004. Assessment of mucosal inflammation and blood flow in response to four weeks intervention with probiotics in patients operated with a J-configurated Ileal-Pouch-Anal-Anastomosis (IPAA). Scand. J. Gastroenterol. (12) 1228-1235.

Laake KO, Line PD, Aabakken L, Løtveit T, Bakka A, Eide J, Røseth A, Grzyb K, Bjørneklett A, Vatn MH. 2003. Assessment of Mucosal inflammation and circulation in response to probiotics in patients operated with ileal pouch anal anastomosis for ulcerative colitis. Scand J Gastroenterol.: 4; 409-414.


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