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Learn More About the Science Behind Probiotics

You Are What You Absorb is an educational web site for healthcare practitioners and others interested in probiotics and wellness.
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Current Research on BB-12®

Examples of published scientific articles, documenting the effect of Chr. Hansen's Bifidobacterium BB-12® (con't):

Laake, K.O., Bjorneklett, A., Bakka, A., Midtvedt, T., Norin, K.E., Eide, T.J., Jacobsen, M.B., Lingaas, E., Axelsen, A.K., Lotveit, T., Vatn, M.H. Influence of fermented milk on clinical state, fecal bacterial counts and biochemical characteristics in patients with ileal- pouch- anal-anastomosis. 1999. Microbial Ecology in Health and Disease, 11: 211-217.

Langhendries, J.P., Detry, J., Van Hees, J., Lamboray, J.M., Darimont, J., Mozin, M. J., Secretin, M.C., Senterre, J. Effect of a fermented infant formula containing viable bifidobacteria on the fecal flora composition and pH of healthy full-term infants. 1995. Journal of Pediatric Gastroenterology and Nutrition, 21: 177-181.

Larsen CN, Nielsen S, Kæstel P, Brockmann E, Bennedsen M, Christensen HR, Eskesen DC, Jacobsen BL, Michaelsen KF. 2006. Dose-response study of probiotic bacteria Bifidobacterium animalis subsp. lactis BB-12 and Lactobacillus paracasei subsp. paracasei CRL-341 in healthy young adults. European Journal of Clinical Nutrition 60 (11): p. 1284-1293.

Matsumoto M. and Benno Y. Consumption of Bifidobacterium lactis LKM512 yogurt reduces gut mutagenicity by increasing gut polyamine contents in healthy adult subjects. Mutation Research 2004. 568; 147-153.

Matsumoto M., H. Ohishi, Y. Benno. 2001. Impact of LKM512 yoghurt on improvement of intestinal environment of the elderly. FEMS Immunology and Medical Microbiology, 31, 181-186.

Matsumoto, M., T. Tadenuma, K. Nakamure, H. Kume, T. Imai, R. Kihara, M. Watanabe and Y. Benno. 2000. Effect of Bifidobacterium lactis LKM 512 yoghurt on fecal microflora in middle to old aged persons.Microbial Ecology in Health and Disease, 12, 77-80.

Mohan R, Koebnick C, Schildt J, Schmidt S, Mueller M, Possner M, Radke M, Blaut M. 2006. Effects of Bifidobacterium lactis BB12 supplementation on intestinal microbiota of preterm infants: a double-blind placebo controlled randomized study. J. Clin. Microbiol. E-pub.

Nord, C.E., Lidbeck, A., Orrhange, K., Sjostedt, S. Oral supplementation with lactic acid bacteria during intake of clindamycin. 1997. Clinical Microbiology and Infection, 3 (1): 124-132.

Nopchinda S, Varavithya W, Phuapradit P, Sangchai R, Suthutvoravut U, Chantraruksa V, Haschke F. 2002. Effect of Bifidobacterium Bb12 with or without Streptococcus thermophilus supplemented formula on nutritional status. J Med Assoc Thai; 85 (suppl 4) 1225-1231

Obradovic, D., Curic, M., Ivanovic, M., Trbojevic, B., Djordjevic, M. 1996. Probiotic function of the fermented milk Jogurt Plus. FEMS Conference (Fifthe Symposium on Lactic Acid Bacteria), Holland, Sept. 8-12.

Phuapradit P, W Varavithya, K Vathanophas, R Sangchai, A Podhipak, U Suthutvoravut, S Nopchinda, V Chantraruksa, F Haschke. 1999. reduction of rotavirus infection in children receiving bifidobacteria-supplemented formula. J. Med. Assoc. Thai. 82, 43-48.

Rautava S, Arvilommi H, Isolauri E. 2006. Specific probiotics in enhancing maturation of IgA responses in formula-fed infants. Pediatric Research 60(2): 222-225.

Reddy BS, MacFie J, Gatt M, Larsen CN, Jensen SS, Leser TD. Randomized clinical trial of effect of synbiotics, neomycin and mechanical bowel preparation on intestinal barrier function in patients undergoing colectomy. Br J Surgery 2007;94:In press

Saavedra JM, Abi-Hanna A, Moore N, Yolken, RH. 2004. Long-term consumption of infant formulas containing live probiotic bacteria: tolerance and safety, Am J Clin Nutr 79: 261-267.

Saavedra, J., Abi-Hanna, A., Moore, N., Yolken, R. Effect of long term consumption of infant formulas with bifidobacteria and S. thermophilus on stool patterns and diaper rash in infants. 1998. J Pediatr Gastroenterol Nutr, 27 (4): 483.

Saavedra, J.M., Bauman, N.A., Oung, I., Perman, J.A., Yolken, R.H. Feeding of Bifidobacterium bifidum and Streptococcus thermophilus to infants in hospital for prevention of diarrhea and shedding of rotavirus. 1994. The Lancet, 344: 1046-1049.

Sagen, O.B. Treatment of functional disturbance in the intestine by administration of lactic acid bacteria. 1989. Internal report.

Schiffrin, E.J., Brassart, D., Servin, A.L., Rochat, F., Donnet-Hughes, A. Immune modulation of blood leucocytes in humans by lactic acid bacteria: criteria for strain selection. 1997. Am J Clin Nutr 66: 515S-520S.

Schiffrin, E.J., Rochat, F., Link-Amster, H., Aeschlimann, J.M., Donnet-Hughes, A. Immunomodulation of human blood cells following the ingestion of lactic acid bacteria. 1995. Journal of Dairy Science, 78: 491-497.

Sheu BY, Cheng H-C, Kao A-W, Wang S-T, Yang Y-J, Yang H-B, Wu J-J. 2006. Pretreatment with Lactobacillus- and Bifidobacterium-containing yogurt can improve the efficacy of Quadruple therapy in eradicating residual Helicobacter pylori infection after failed triple therapy. Am J Clin Nutr 83: 864-9.

Sullivan Å, Barkholt L, Nord CE. 2003. Lactobacillus acidophilus, Bifidobacterium lactis and Lactobacillus F19 prevent antibiotic- associated ecological disturbances of Bacteroides fragilis in the intestine. Journal of Antimicrobial Chemotherapy, 52, 308-311.

Sheu BS, J Wu, CY Lo, HW Wu, JH Chen, YS Lin & MD Lin. 2002. Impact of supplement with Lactobacillus- and Bifidobacterium-containing yoghurt on triple therapy for Helicobacter pylori eradication. Aliment. Pharmacol. Ther. 16, 1669-1675.

Virta, P., Otterström, K., Niemi, L., Wieser-Aho, M.-T., Lähteenmäki, A.-L., Leppänen, T. The effect of a preparation containing freeze-dried lactic acid bacteria on lactose intolerance. 1993. External report

Wang KY, Li SN, Liu CS, Perng DS, Su YC, Wu DC, Jan CM, Lai CH, Wang TN, Wang WM. 2004. Effects of ingesting Lactobacillus- and Bifidobacterium-containing yoghurt in subjects with colonized Helicobacter pylori. Am. J. Clin. Nutr. 80; 737-41.

Weizman Z, Alsheikh A. 2006. Safety and Tolerance of a Probiotic formula in early infancy comparing two probiotic agents: A pilot study. J Am Coll Nutr. 25(5):415-9.

Wildt S, Munck LK, Vinter-Jensen L, Hansen BF, Nordgaard-Lassen I, Christensen S, Avnstroem S, Rasmussen SN, Rumessen J. 2006. Probiotic treatment of collagenous colitis: A randomized, double-blind, placebo-controlled trial with L. acidophilus and Bifidobacterium animalis subsp. lactis. Inflamm Bowel Dis 12 (5): 395-401.