e-Newsletter Sign Up
My Account

Learn More About the Science Behind Probiotics

You Are What You Absorb is an educational web site for healthcare practitioners and others interested in probiotics and wellness.
Bookmark and Share

Current Research on LA-5®

Examples of published scientific articles, documenting the effect of Chr. Hansen's L. acidophilus LA-5®:

Alm, L., Ryd-Kjellen, E., Setterberg, G., Blomquist, L. Effect of a new fermented milk product "CULTURA" on constipation in geriatric patients. 1993. 1st Lactic Acid Bacteria Computer Conference Proceedings. Horizon Scientific Press, Norfolk, England.

Anderson ADG, McNaught CE, MacFie J, Tring I, Barker P, Mitchell CJ. 2003. Randomized clinical trial of multimodal optimization and standard perioperative surgical care. British Journal of Surgery, 90; 1497-1504.

Black, F.T. Placebo-contolled double-blind trial of 4 lactobacilli strains (HIP) used as prophylactic agent against traveller's diarrhea (2 trials). 1996. Report by G. Nirnberger, Bioconsult, GmbH, Austria.

Black, F.T., Andersen, P.L., Laulund, S. Report from a double-blind placebo-controlled trial with HIP against traveler's diarrhea with a new dosage regimen. 1995. Internal report.

Black, F.T., Einarsson, K., Lidbeck, A., Orrhage, K., Nord, C.E. Effect of lactic acid producing bacteria on the human intestinal microflora during ampicillin treatment. 1991. Scand. J. Infect. Dis., 23: 247-254.

Black, F.T., Anderson, P.L., Orskov J., Orskov, F., Gaarslev, K., Laulund, S. Prophylactic efficacy of lactobacilli on traveler's diarrhea. 1989. Travel Medicine, 333-335.

Black, F.T., Laulund, S. A study on the recovery of ingested, encapsulated Lactobacillus acidophilus and Bifidobacteria bifidum from doudenal fluid and faeces. 1988. Chr. Hansen Internal Report.

Gatt M, Anderson ADG, Reddy BS, Hayward-Sampson P, tring IC, MacFie J. 2005. Randomized clinical trial of multimodal optimization of surgical care in patients undergoing major colonic resection. British Journal of Surgery, 92, 1354-1362.

Hilton, E., Isenburg, H.D., Alpenstein, P., France, K., Borenstein, M. Ingestion of yogurt containing Lactobacillus acidophilus as prophylaxis for candidal vaginitis. 1992. Annals of Internal Medicine, 116:353-357.

Jain PK, McNaught CE, Anderson ADG, MacFie J, Mitchell CJ. 2004. Influence of synbiotic containing Lactobacillus acidophilus La5, Bifidobacterium lactic Bb12, Streptococcus thermophilus, Lactobacillus bulgaricus and oligofructose on gut barrier function and sepsis in critically ill patients: a randomised controlled trial. Clinical Nutrition 23; 467-475.

Laake K.O., Bjørneklett A., Aamodt G., Aabakken L., Jacobsen, M., Bakka, A., Vatn, M.H. 2005. Outcome of four weeks intervention with probiotics on symptoms and endoscopic appearance after surgical reconstruction with a J-configurated ileal-pouch-anal-anastomosis in ulcerative colitis. Scandinavian Journal of Gastroenterology (40) 43-51.

Laake, K.O., P.D. Line, K. Grzyb, G. Aamodt, L. Aabakken, A. Røset, A.B. Hvinden, A. Bakka, J. Eide, A. Bjørneklett, M.H. Vatn. 2004. Assessment of mucosal inflammation and blood flow in response to four weeks intervention with probiotics in patients operated with a J-configurated Ileal-Pouch-Anal-Anastomosis (IPAA). Scand. J. Gastroenterol. (12) 1228-1235.



 

Laake KO, Line PD, Aabakken L, Løtveit T, Bakka A, Eide J, Røseth A, Grzyb K, Bjørneklett A, Vatn MH. 2003. Assessment of Mucosal inflammation and circulation in response to probiotics in patients operated with ileal pouch anal anastomosis for ulcerative colitis. Scand J Gastroenterol.: 4; 409-414.

Laake, K.O., Bjorneklett, A., Bakka, A., Midtvedt, T., Norin, K.E., Eide, T.J., Jacobsen, M.B., Lingaas, E., Axelsen, A.K., Lotveit, T., Vatn, M.H. Influence of fermented milk on clinical state, fecal bacterial counts and biochemical characteristics in patients with ileal- pouch- anal-anastomosis. 1999. Microbial Ecology in Health and Disease, 11: 211-217.

Lin. M.-Y., Savaiano, D., Harlander, S. Influence of nonfermented dairy products containing bacterial starter cultures on lactose maldigestion in humans. 1991. J. Dairy Sci,. 74: 87-95.

Nord, C.E., Lidbeck, A., Orrhange, K., Sjostedt, S. Oral supplementation with lactic acid bacteria during intake of clindamycin. 1997. Clinical Microbiology and Infection, 3 (1): 124-132.

Obradovic, D., Curic, M., Ivanovic, M., Trbojevic, B., Djordjevic, M. 1996. Probiotic function of the fermented milk Jogurt Plus. FEMS Conference (Fifthe Symposium on Lactic Acid Bacteria), Holland, Sept. 8-12.

Reddy BS, MacFie J, Gatt M, Larsen CN, Jensen SS, Leser TD. Randomized clinical trial of effect of synbiotics, neomycin and mechanical bowel preparation on intestinal barrier function in patients undergoing colectomy. Br J Surgery 2007;94:In press

Sagen, O.B. Treatment of functional disturbance in the intestine by administration of lactic acid bacteria. 1989. Internal report.

Sheu BY, Cheng H-C, Kao A-W, Wang S-T, Yang Y-J, Yang H-B, Wu J-J. 2006. Pretreatment with Lactobacillus- and Bifidobacterium-containing yogurt can improve the efficacy of Quadruple therapy in eradicating residual Helicobacter pylori infection after failed triple therapy. Am J Clin Nutr 83: 864-9.

Sheu BS, J Wu, CY Lo, HW Wu, JH Chen, YS Lin & MD Lin. 2002. Impact of supplement with Lactobacillus- and Bifidobacterium-containing yoghurt on triple therapy for Helicobacter pylori eradication. Aliment. Pharmacol. Ther. 16, 1669-1675.

Virta, P., Otterström, K., Niemi, L., Wieser-Aho, M.-T., Lähteenmäki, A.-L., Leppänen, T. The effect of a preparation containing freeze-dried lactic acid bacteria on lactose intolerance. 1993. External report

Wang KY, Li SN, Liu CS, Perng DS, Su YC, Wu DC, Jan CM, Lai CH, Wang TN, Wang WM. 2004. Effects of ingesting Lactobacillus- and Bifidobacterium-containing yoghurt in subjects with colonized Helicobacter pylori. Am. J. Clin. Nutr. 80; 737-41.

Wildt S, Munck LK, Vinter-Jensen L, Hansen BF, Nordgaard-Lassen I, Christensen S, Avnstroem S, Rasmussen SN, Rumessen J. 2006. Probiotic treatment of collagenous colitis: A randomized, double-blind, placebo-controlled trial with L. acidophilus and Bifidobacterium animalis subsp. lactis. Inflamm Bowel Dis 12 (5): 395-401.